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| 生化科研试剂 >> 抗体产品 >> 一抗 |
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HOXB4
HoxB4 |
| 别 名： |
HOXB4 antibody, HOX-2.6 antibody, HOX2 antibody, HOX2F antibody, Homeobox protein Hox-B4 antibody, Homeobox protein Hox-2.6 antibody, Homeobox protein Hox-2F antibody |
| 货号 |
品名 |
规格 |
包装 |
单价 |
货期 |
库存 |
| 1227178963 |
HOXB4 |
|
100ul |
询价 |
现货 |
3天 |
| 提示信息：偏远地区如新疆西藏宁夏甘肃等地可能无法运送液体，下单前请联系客服。 |
| 性 状： |
【产品类型】Rabbit Monoclonal Antibody
【反应特异性】Human , Mouse , Rat
【克隆 ID】EPR1917
【用途】WB , ICC , IP
【产品性状】
【阳性对照】
【产品浓度】
【细胞定位】
【抗原分子量】34kDa |
| 质量标准： |
【产品介绍】Homeobox transcription factors (Hox) are
highly conserved developmental proteins that are involved
in embryonic and early hematopoietic
development. Specifically, Homeobox B4 (HoxB4) is
a transcription factor that is involved in the
developmental regulation of specific positional
identities on the anterior-posterior axis of cells. Like
all members of the HOX family, HoxB4 is abundantly
expressed in primitive hematopoietic stem cells (HSC),
but then it declines with lineage-specific
terminal differentiation (1). In HSC's, stem
cell self-renewal activity is regulated by USF1/2 binding
to HoxB4, where binding possibly favors stem
cell self-renewal instead of cell differentiation. Jun-B
and Fra-1 have been linked to key mediators during
cell proliferation and differentiation induced by
HoxB4, which leads to an increase in expression of Cyclin
D1 and G1 shortening (2).Recommended Applications
WB, ICC, IP
Applications and Recommended Dilution Factors
WB: 1:1,000 - 10,000
ICC: 1:100 - 250
IP: 1:10 - 100
Species Reactivity *
Human, Mouse, Rat
*Species cross-reactivity is based on WB analysis. Products Data Western blot analysis on (A) K562, (B) Jurkat, (C)
RAW 264.7, and (D) PC-12 cell lysates using
anti-HoxB4 RabMAb (cat. #5110-1). Immunofluorescent staining of NCCIT cells using
anti-HoxB4 RabMAb (cat. #5110-1). Specificity
A synthetic peptide corresponding to residues in human
HoxB4 was used as an immunogen. |
| 贮 存： |
Store at -20 °C. Antibody buffer, 0.01% sodium azide,
50% Glycerol and 0.05% BSA. Stable for 12 months from date
of receipt |
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